Thirty years of ‘quiet eye’ with etafilcon A contact lenses
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articles analysedNathan Efrona, Noel A. Brennanb, Robin L. Chalmersc, Lyndon Jonesd, Charis Laub, Philip B. Morgane, Jason J. Nicholsf, Loretta B. Szczotka-Flynng, Mark D.Willcoxh a. Institute of Health and Biomedical Innovation, School of Optometry and Vision Science, Queensland University of Technology, Australia; b. Johnson & Johnson Vision, Inc, Jacksonville, FL, USA; c. Clinical Trial Consultant, Atlanta, GA, USA; d. Centre for Ocular Research & Education (CORE), School of Optometry & Vision Science, University of Waterloo, Waterloo, ON, Canada; e. Eurolens Research, Division of Pharmacy and Optometry, The University of Manchester, UK; f. The University of Alabama at Birmingham, School of Optometry, Birmingham, AL, USA; g. University Hospitals Eye Institute, University Hospitals Cleveland Medical Center, Department of Ophthalmology & Visual Sciences, Case Western Reserve University, Cleveland, OH, USA; h. School of Optometry and Vision Science, University of New South Wales, Sydney, Australia
Led by Professor Nathan Efron, a team of eminent researchers have recently come together to summarise the extensive body of research, conducted by themselves and others, that sets out the considerable performance benefits of etafilcon A contact lenses (the material behind 1-DAY ACUVUE® MOIST) conducted over the last three decades. Key findings in this review are:
Low inflammatory response
and infection risk profile during daily wear. This may be related to the low modulus and the naturally protective anti-microbial non- denatured lysozyme absorbed into the lens from the tear fluid (with in-vitro testing).2*
Equivalent levels of corneal oxygenation
compared to silicone hydrogel materials are maintained during daily wear of low to medium powered etafilcon A lenses.
The daily corneal de-swelling process is not impeded and clinically significant changes in ocular health are not induced.
Looking at material type
hydrogel lenses in general do not appear to show differences in dryness and discomfort compared to hydrogel materials.
Etafilcon A remains the most widely used hydrogel material today and remains an important alternative for daily wear in modern contact lens practice.‡
1-DAY ACUVUE® MOIST
In a year-long observational study of 570 registered patients wearing
1-DAY ACUVUE® MOIST, the rate of non-serious contact lens related
adverse events reported was 0.6%/year. There were no serious adverse
events and no symptomatic infiltrative events. However, serious adverse
events have been reported at very low rates outside of this study.3*
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